Childhood friends Julián (Ricardo Darín) and Tomás (Javier Cámara) were once inseparable. Eventually, the two have lost sight of their friendship. While the divorced Julián remained in Spain where he has lived through the highs and lows of an acting career, the teacher Tomás emigrated to Canada, where he has built up a peaceful existence together with his job, his wife and his children. After a reunion one day in Madrid, their friendship survived once again, as if it had never fallen asleep. Together the two spend a few wonderful days in the city full of nostalgic memories and unforgettable experiences -knowing that this will probably be their last reunion because Julián has been diagnosed terminally ill with cancer.