A native of Savannah, Georgia, Huxsie Scott is regarded as one of the greatest jazz/blues artists ever to live and perform in the Savannah Coastal Area. Huxsie began her career as a jazz vocalist and has performed with many of the area's premiere jazz ensembles and symphony orchestras. Huxsie was a featured opener for such jazz greats as the late Lionel Hampton and McCoy Tyner. She was the original vocalist for the Savannah Jazz Orchestra and worked for a number of years as the featured vocalist for jazz great and Savannah resident, bassist Ben Tucker.
In 2004 Huxsie was inducted into the Savannah Tribune Gospel Hall Of Fame and was voted Best Female Contemporary Gospel Artist by the listeners of WSOK/Clear Channel Radio. In 2005, she was inducted into the Coastal Jazz Association's Hall of Fame.
Currently, she is a featured performer at the historic Savannah Theatre.